JOURNAL OF APPLIED TOXICOLOGY
ISSN:0260-437X

JOURNAL OF APPLIED TOXICOLOGY

J APPL TOXICOL
学科领域:医学
是否预警:不在预警名单内
是否OA:
录用周期:平均1月
新锐分区:医学4区
年发文量:157
影响因子:2.8
JCR分区:Q2

基本信息

《应用毒理学杂志》发表同行评审的原创评论和假设驱动的研究文章,涉及药物和化学品在分子、细胞、组织、靶器官和全身水平的体内(通过所有相关暴露途径)和体外/离体毒性的机制、基础和应用研究。涵盖毒理学的所有方面(包括但不限于纳米毒理学、基因组学和蛋白质组学、致畸作用、致癌作用、诱变、生殖和内分泌毒理学、毒性病理学、靶器官毒性、系统毒性(例如免疫毒性)、神经行为毒理学、机制研究、生化和分子毒理学、新型生物标志物、药代动力学/PBPK、风险评估和环境健康研究),并强调论文明确应用于人类健康,和/或推进机械理解和/或提供重大贡献和影响,他们的领域。
0260-437XSCIE/Scopus收录
2.8
3
2026年3月发布
点击查看历史分区趋势    >
大类学科小类学科Top期刊综述期刊
医学4区
TOXICOLOGY 毒理学
3区
N/A
WOS期刊SCI分区  2024-2025最新升级版
按JIF指标学科分区收集子录JIF分区JIF排名百分位
学科:TOXICOLOGY
SCIE
Q2
53/106
按JCR指标学科分区收集子录JCR分区JCR排名百分位
学科:TOXICOLOGY
SCIE
Q3
56/106
76
157
26%约50%平均1月-医学-毒理学
3.6%
时间预警情况
2026年03月发布的新锐学术版不在预警名单中
2025年03月发布的2025版不在预警名单中
2024年02月发布的2024版不在预警名单中
2023年01月发布的2023版不在预警名单中
2021年12月发布的2021版不在预警名单中
2020年12月发布的2020版不在预警名单中
79.62%13.81%0.53%
CiteScore:6.60
SJR:0.745
SNIP:0.736
学科类别分区排名百分位
大类:Pharmacology, Toxicology and Pharmaceutics
小类:Toxicology
Q2
36 / 131

期刊高被引文献

Potential health impact of environmental micro‐ and nanoplastics pollution
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3915
Comparison of the metabolism of 10 chemicals in human and pig skin explants
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3730
The toxic potential of a fourth‐generation E‐cigarette on human lung cell lines and tissue explants
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3799
Electronic cigarette liquid exposure induces flavor‐dependent osteotoxicity and increases expression of a key bone marker, collagen type I
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3777
Single wall and multiwall carbon nanotubes induce different toxicological responses in rat alveolar macrophages
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3765
The toxicity of ZnO nanomaterials to HepG2 cells: the influence of size and shape of particles
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3712
Zinc oxide nanoparticles induced gene mutation at the HGPRT locus and cell cycle arrest associated with apoptosis in V‐79 cells
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3763
Vanadium compounds and cellular death mechanisms in the A549 cell line: The relevance of the compound valence
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3746
Rebaudioside A administration prevents experimental liver fibrosis: an in vivo and in vitro study of the mechanisms of action involved
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3797
The NTP Report on Carcinogens: A valuable resource for public health, a challenge for regulatory science
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3894
Regulation of NRF2, AP‐1 and NF‐κB by cigarette smoke exposure in three‐dimensional human bronchial epithelial cells
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3761
Toxicological safety assessment of the human‐identical milk oligosaccharide 3′‐sialyllactose sodium salt
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3824
Predicting the cytotoxicity of chemicals using ensemble learning methods and molecular fingerprints
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3785
In vitro and in silico hormonal activity studies of di‐(2‐ethylhexyl)terephthalate, a di‐(2‐ethylhexyl)phthalate substitute used in medical devices, and its metabolites
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3792
Cytotoxic and proinflammatory responses induced by ZnO nanoparticles in in vitro intestinal barrier
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3800
Comprehensive lipid profiling of bleomycin‐induced lung injury
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3758
Repeated injection of KMRC011, a medical countermeasure for radiation, can cause adverse health effects in cynomolgus monkeys
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3719
In silico prediction of chemical reproductive toxicity using machine learning
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3772
An epigenome‐wide DNA methylation study of workers with an occupational exposure to lead
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3816
Oximes as pretreatment before acute exposure to paraoxon
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3835
In vitro toxicity screening of magnetite nanoparticles by applying mesenchymal stem cells derived from human umbilical cord lining
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3819
Cytotoxicity profile of pristine graphene on brain microvascular endothelial cells
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3786
Direct activation of aryl hydrocarbon receptor by benzo[a]pyrene elicits T‐helper 2‐driven proinflammatory responses in a mouse model of allergic dermatitis
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3782
Cr(VI)‐induced genotoxicity and cell cycle arrest in human osteoblast cell line MG‐63
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3793
Nifedipine toxicity is exacerbated by acetyl l‐carnitine but alleviated by low‐dose ketamine in zebrafish in vivo
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3901
Effects of co‐exposure of lipopolysaccharide and β‐glucan (Zymosan A) in exacerbating murine allergic asthma associated with Asian sand dust
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3759
Establishment of a high‐sensitivity reporter system in mammalian cells for detecting juvenoids using juvenile hormone receptors of Daphnia pulex
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3713
Prenatal exposure to PCBs in Cyp1a2 knock‐out mice interferes with F1 fertility, impairs long‐term potentiation, reduces acoustic startle and impairs conditioned freezing contextual memory with minimal transgenerational effects
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3751
Triptolide‐induced hepatotoxicity via apoptosis and autophagy in zebrafish
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3837
Assessment of sublethal ecotoxicity of solvents on larvae of a model native amphibian (Lithobates pipiens)
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3920
CYP3A4/5 mediates the metabolic detoxification of humantenmine, a highly toxic alkaloid from Gelsemium elegans Benth.
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3813
In vitro genotoxicity assessment of an oxidized dextrin‐based hydrogel for biomedical applications
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3754
Food‐grade titanium dioxide (E171) by solid or liquid matrix administration induces inflammation, germ cells sloughing in seminiferous tubules and blood‐testis barrier disruption in mice
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3842
The glycolytic shift was involved in CdTe/ZnS quantum dots inducing microglial activation mediated through the mTOR signaling pathway
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3912
Cell‐specific immune‐modulation of cadmium on murine macrophages and mast cell lines in vitro
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3788
Liver safety evaluation of endothelin receptor antagonists using HepatoPac®: A single model impact assessment on hepatocellular health, function and bile acid disposition
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3805
Acute toxicity of intratracheal arsenic trioxide instillation in rat lungs
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3841
A microarray‐based comparative analysis of gene expression profiles in thyroid glands in amphibian metamorphosis: differences in effects between chemical exposure and food restriction
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3791
An updated weight of evidence approach for deriving a health‐based guidance value for 4‐nonylphenol
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3661
Searching for tryptase in the RBL‐2H3 mast cell model: Preparation for comparative mast cell toxicology studies with zebrafish
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3738
The role of metabolism in the developmental toxicity of polycyclic aromatic hydrocarbon‐containing extracts of petroleum substances
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3906
Growth‐promoting effects of low‐level butyl benzyl phthalate exposure on human neuroblastoma SH‐SY5Y cells
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3803
Comparison of tris(2‐ethylhexyl) phosphate and di(2‐ethylhexyl) phosphoric acid toxicities in a rat 28‐day oral exposure study
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3930
The interplay between chemical speciation and physiology determines the bioaccumulation and toxicity of Cu(II) and Cd(II) to Caenorhabditis elegans
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3718
Issue Information
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3685
Markers of oxidative‐nitrosative stress induced by artesunate are followed by clastogenic and aneugenic effects and apoptosis in human lymphocytes
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3826
Issue Information
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3687
Assessment of the 4‐week repeated‐dose oral toxicity and genotoxicity of GHX02
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3902
Issue Information
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3673
Derivation of an occupational exposure limit for diacetyl using dose‐response data from a chronic animal inhalation exposure study
来源期刊:Journal of Applied ToxicologyDOI:10.1002/jat.3757

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