Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathway
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01656-9
Andrographolide enhances hippocampal BDNF signaling and suppresses neuronal apoptosis, astroglial activation, neuroinflammation, and spatial memory deficits in a rat model of chronic cerebral hypoperfusion
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01672-9
Gastroprotective effect of cilostazol against ethanol- and pylorus ligation–induced gastric lesions in rats
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01699-y
Triglyceride-lowering effect of the aldose reductase inhibitor cemtirestat—another factor that may contribute to attenuation of symptoms of peripheral neuropathy in STZ-diabetic rats
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01769-1
Sodium butyrate recovers high-fat diet-fed female Wistar rats from glucose dysmetabolism and uric acid-associated cardiac tissue damage
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01679-2
Aldosterone stimulation mediates cardiac metabolism remodeling via Sirt1/AMPK signaling in canine model
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01641-2
Chrysophanol exhibits anti-cancer activities in lung cancer cell through regulating ROS/HIF-1a/VEGF signaling pathway
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01746-8
Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01673-8
Ferulic acid ameliorates doxorubicin-induced cardiac toxicity in rats
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01623-4
PHD-2 activation: a novel strategy to control HIF-1α and mitochondrial stress to modulate mammary gland pathophysiology in ER+ subtype
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01658-7
Effects of the solid lipid nanoparticle of carvacrol on rodents with lung injury from smoke inhalation
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01731-1
The deafness gene GSDME: its involvement in cell apoptosis, secondary necrosis, and cancers
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01674-7
Chrysophanol suppresses growth and metastasis of T cell acute lymphoblastic leukemia via miR-9/PD-L1 axis
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01778-0
Effect of oleuropein on morphine-induced hippocampus neurotoxicity and memory impairments in rats
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01678-3
MLC901 during sleep deprivation rescues fear memory disruption in rats
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-018-01612-z
Evaluation of the pharmacological involvement of ATP-sensitive potassium (KATP) channels in the antidepressant-like effects of topiramate on mice
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01636-z
Effects of cholecalciferol on behavior and production of reactive oxygen species in female mice subjected to corticosterone-induced model of depression
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01714-2
Role of glucagon-like peptides in inflammatory bowel diseases—current knowledge and future perspectives
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01698-z
Small molecules for modulating the localisation of the water channel aquaporin-2—disease relevance and perspectives for targeting local cAMP signalling
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01686-3
Apoptotic effect of fluoxetine through the endoplasmic reticulum stress pathway in the human gastric cancer cell line AGS
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01739-7
Antimelanoma activity of perphenazine and prochlorperazine in human COLO829 and C32 cell lines
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01668-5
Triggering of eryptosis, the suicidal erythrocyte death, by phenoxodiol
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01681-8
Influence of intranasal exposure of MPTP in multiple doses on liver functions and transition from non-motor to motor symptoms in a rat PD model
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01715-1
The antiobese effect of AT1 receptor blockade is augmented in mice lacking Mas
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01643-0
Resveratrol and quercetin attenuate depressive-like behavior and restore impaired contractility of vas deferens in chronic stress-exposed rats: involvement of oxidative stress and inflammation
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01781-5
Coptisine ameliorates renal injury in diabetic rats through the activation of Nrf2 signaling pathway
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01710-6
The phospholipase C inhibitor U73122 is a potent agonist of the polymodal transient receptor potential ankyrin type 1 (TRPA1) receptor channel
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01722-2
Metamizole and the risk of drug-induced agranulocytosis and neutropenia in statutory health insurance data
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01774-4
Functional and structural characterisation of common cytochrome P450 2D6 allelic variants—roles of Pro34 and Thr107 in catalysis and inhibition
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01651-0
Mitochondrial dysfunction plays a key role in the abrogation of cardioprotection by sodium hydrosulfide post-conditioning in diabetic cardiomyopathy rat heart
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01733-z
Which phosphodiesterase can decrease cardiac effects of 5-HT4 receptor activation in transgenic mice?
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01653-y
Biphasic effects of 5-HT1A agonism on impulsive responding are dissociable from effects on anxiety in the variable consecutive number task
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01684-5
Lacidipine attenuates reserpine-induced depression-like behavior and oxido-nitrosative stress in mice
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01667-6
Pretreatment with vildagliptin boosts ischemic-postconditioning effects on cardioprotection and expression profile of genes regulating autophagy and mitochondrial fission/fusion in diabetic heart with reperfusion injury
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01660-z
Protective effect of apigenin on d-galactosamine/LPS-induced hepatocellular injury by increment of Nrf-2 nucleus translocation
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01760-w
Carvacrol suppresses learning and memory dysfunction and hippocampal damages caused by chronic cerebral hypoperfusion
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01754-8
Apoptotic effects of norfloxacin on corneal endothelial cells
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01711-5
NPPB prevents postoperative peritoneal adhesion formation by blocking volume-activated Cl− current
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01740-0
Histone deacetylase inhibitor CG200745 ameliorates high-fat diet-induced hypertension via inhibition of angiotensin II production
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01749-5
Medial prefrontal cortex diclofenac-induced antinociception is mediated through GPR55, cannabinoid CB1, and mu-opioid receptors of this area and periaqueductal gray
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01735-x
Amitriptyline accumulation in tissues after coated activated charcoal hemoperfusion—a randomized controlled animal poisoning model
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01669-4
Effect of syringic acid and syringaldehyde on oxidative stress and inflammatory status in peripheral blood mononuclear cells from patients of myocardial infarction
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01768-2
cAMP guided his way: a life for G protein-mediated signal transduction and molecular pharmacology—tribute to Karl H. Jakobs
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01650-1
Activation of death receptor, DR5 and mitochondria-mediated apoptosis by a 3,4,5-trimethoxybenzyloxy derivative in wild-type and p53 mutant colorectal cancer cell lines
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01730-2
Isoespintanol, a monoterpene isolated from oxandra cf xylopioides, ameliorates the myocardial ischemia-reperfusion injury by AKT/PKCε/eNOS-dependent pathways
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01761-9
The energy-saving effect of a new myosin activator, omecamtiv mecarbil, on LV mechanoenergetics in rat hearts with blood-perfused isovolumic contraction model
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01685-4
Compound C attenuates NLRP3 inflammasome despite AMPK knockdown in LPS plus palmitate-induced THP-1 cells
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01712-4
Effect of infliximab, a tumor necrosis factor-alpha inhibitor, on doxorubicin-induced nephrotoxicity in rats
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01719-x
Antidepressant-like effect and toxicological parameters of extract and withanolides isolated from aerial parts of Solanum capsicoides All. (Solanaceae)
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01648-9
3-Amidinophenylalanine-derived matriptase inhibitors can modulate hepcidin production in vitro
来源期刊:Naunyn-Schmiedeberg s Archives of PharmacologyDOI:10.1007/s00210-019-01743-x