CPT-Pharmacometrics & Systems Pharmacology

NONMEM Tutorial Part II: Estimation Methods and Advanced Examples

Consideration of a Credibility Assessment Framework in Model‐Informed Drug Development: Potential Application to Physiologically‐Based Pharmacokinetic Modeling and Simulation

Physiologically‐Based Pharmacokinetic Modeling vs. Allometric Scaling for the Prediction of Infliximab Pharmacokinetics in Pediatric Patients

Physiologically‐Based Pharmacokinetic Modeling Approach to Predict Rifampin‐Mediated Intestinal P‐Glycoprotein Induction

Expanded Physiologically‐Based Pharmacokinetic Model of Rifampicin for Predicting Interactions With Drugs and an Endogenous Biomarker via Complex Mechanisms Including Organic Anion Transporting Polypeptide 1B Induction

Reproducibility of Quantitative Systems Pharmacology Models: Current Challenges and Future Opportunities

Quantitative Systems Pharmacology for Neuroscience Drug Discovery and Development: Current Status, Opportunities, and Challenges

Applications of Quantitative Systems Pharmacology in Model‐Informed Drug Discovery: Perspective on Impact and Opportunities

Population Pharmacokinetics of Ipilimumab in Combination With Nivolumab in Patients With Advanced Solid Tumors

Physiologically‐Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter–Mediated Interactions Between Metformin and Cimetidine

A Theoretical Physiologically‐Based Pharmacokinetic Approach to Ascertain Covariates Explaining the Large Interpatient Variability in Tacrolimus Disposition

A Comprehensive Framework for Physiologically‐Based Pharmacokinetic Modeling in Matlab

Children Are Not Small Adults, but Can We Treat Them As Such?

A Survey of Software Tool Utilization and Capabilities for Quantitative Systems Pharmacology: What We Have and What We Need

Quantitative Systems Pharmacology and Empirical Models: Friends or Foes?

Current Scientific Considerations to Verify Physiologically‐Based Pharmacokinetic Models and Their Implications for Locally Acting Products

A Flexible Approach for Context‐Dependent Assessment of Quantitative Systems Pharmacology Models

Linking Tumor Growth Dynamics to Survival in Ipilimumab‐Treated Patients With Advanced Melanoma Using Mixture Tumor Growth Dynamic Modeling

In Silico Methods for Development of Generic Drug–Device Combination Orally Inhaled Drug Products

Concentration–QT Modeling Following Inhalation of the Novel Inhaled Phosphodiesterase‐4 Inhibitor CHF6001 in Healthy Volunteers Shows an Absence of QT Prolongation

Recommendations for the Design of Clinical Drug–Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically‐Based Pharmacokinetic Model

Pharmacokinetics of Capecitabine and Four Metabolites in a Heterogeneous Population of Cancer Patients: A Comprehensive Analysis

Evaluating the Role of Janus Kinase Pathways in Platelet Homeostasis Using a Systems Modeling Approach

Evaluation of QT Liability for PF‐05251749 in the Presence of Potential Circadian Rhythm Modification

Model Informed Drug Development and Regulation in China: Challenges and Opportunities

Open Source Pharmacokinetic/Pharmacodynamic Framework: Tutorial on the BioGears Engine

Development of a Parsimonious Design for Optimal Classification of Exclusive Breastfeeding

Iberoamerican Pharmacometrics Network Congress 2018 Report: Fostering Modeling and Simulation Approaches for Drug Development and Regulatory and Clinical Applications in Latin America

The Mathematical and Computational Sciences Special Interest Group of the International Society of Pharmacometrics

Exposure–Response‐Based Product Profile–Driven Clinical Utility Index for Ipatasertib Dose Selection in Prostate Cancer

Quantitative Systems Pharmacology Model of a Masked, Tumor‐Activated Antibody

Optimal Scheduling of Bevacizumab and Pemetrexed/Cisplatin Dosing in Non‐Small Cell Lung Cancer

Blood‐Based Biomarkers of Quinpirole Pharmacology: Cluster‐Based PK/PD and Metabolomics to Unravel the Underlying Dynamics in Rat Plasma and Brain

Industrialization of Quantitative Systems Pharmacology

Incorporating Placebo Response in Quantitative Systems Pharmacology Models

Probenecid‐Boosted Tenofovir: A Physiologically‐Based Pharmacokinetic Model‐Informed Strategy for On‐Demand HIV Preexposure Prophylaxis

Time‐to‐Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine‐Citrulline‐Monomethylauristatin E Antibody–Drug Conjugates

Could Postnatal Age–Related Uridine Diphosphate Glucuronic Acid Be a Rate‐Limiting Factor in the Metabolism of Morphine During the First Week of Life?

What Can Be Learned From Crowdsourced Population Asparagus Urinary Odor Kinetics?

Population Pharmacokinetic/Pharmacodynamic Modeling of Methylprednisolone in Neonates Undergoing Cardiopulmonary Bypass

QSP and PBPK Modeling with mrgsolve: A Hands-on Tutorial.

Antibodies to Modulate Surface Receptor Systems Are Often Bivalent and Must Compete in a Two‐Dimensional Cell Contact Region

A Citrulline‐Based Translational Population System Toxicology Model for Gastrointestinal‐Related Adverse Events Associated With Anticancer Treatments

Causa Nostra: The Potentially Legitimate Business of Drawing Causal Inferences From Observational Data

ATLAS mPBPK: A MATLAB‐Based Tool for Modeling and Simulation of Minimal Physiologically‐Based Pharmacokinetic Models

Model‐Informed Assessment of Anti‐Infectives for Young Children in Low‐ and Middle‐Income Countries